GRK 1 Polyclonal Antibody

CAT: 0749-ABP51477-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP51477-01Size:30 µL
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Background
GRK1 encodes a member of the guanine nucleotide-binding protein (G protein) -coupled receptor kinase subfamily of the Ser/Thr protein kinase family. Rhodopsin kinase phosphorylates rhodopsin and initiates its deactivation. Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi type-2) .
Description
Rabbit Anti-GRK 1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
GRK1; RHOK; Rhodopsin kinase; RK; G protein-coupled receptor kinase 1
Gene ID
6011
Accession Number
Q15835
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from human GRK 1 around the non-phosphorylation site of S21
Clonality
Polyclonal
Tag
Rhodopsin kinase
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
63kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
GRK 1 Polyclonal Antibody detects endogenous levels of GRK 1 protein.
Observed Molecular Weight
63
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200
Other Product Names
GRK1; RHOK; Rhodopsin kinase; RK; G protein-coupled receptor kinase 1
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q15835
Isotype
Rabbit IgG

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