Products for Research Use Only

GRB14 Polyclonal Antibody

CAT: 0749-ABP51474-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP51474-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Growth factor receptor-bound protein 14 belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. GRB14 encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Growth factor receptor-bound protein 14 likely has an inhibitory effect on receptor tyrosine kinase signaling and, in particular, on insulin receptor signaling. GRB14 may play a role in signaling pathways that regulate growth and metabolism. Alternative splicing results in multiple transcript variants.
Description
Rabbit Anti-GRB14 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
GRB14; Growth factor receptor-bound protein 14; GRB14 adapter protein
Gene ID
2888
Accession Number
Q14449
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the Internal region of human GRB14 at AA range: 50-130
Clonality
Polyclonal
Tag
Growth factor receptor-bound protein 14
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
61kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
GRB14 Polyclonal Antibody detects endogenous levels of GRB14 protein.
Observed Molecular Weight
61
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200
Other Product Names
GRB14; Growth factor receptor-bound protein 14; GRB14 adapter protein
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q14449
Isotype
Rabbit IgG

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