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GAK Polyclonal Antibody

CAT: 0749-ABP51394-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP51394-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
In all eukaryotes, the cell cycle is governed by cyclin-dependent protein kinases (CDKs), whose activities are regulated by cyclins and CDK inhibitors in a diverse array of mechanisms that involve the control of phosphorylation and dephosphorylation of Ser, Thr or Tyr residues. Cyclins are molecules that possess a consensus domain called the cyclin box. In mammalian cells, 9 cyclin species have been identified, and they are referred to as cyclins A through I. Cyclin G is a direct transcriptional target of the p53 tumor suppressor gene product and thus functions downstream of p53. GAK is an association partner of cyclin G and CDK5. Alternative splicing results in multiple transcript variants encoding different isoforms.
Description
Rabbit Anti-GAK Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
GAK; Cyclin-G-associated kinase
Gene ID
2580
Accession Number
O14976
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from the N-terminal region of human GAK at AA range: 70-150
Clonality
Polyclonal
Tag
Cyclin-G-associated kinase
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
144kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
GAK Polyclonal Antibody detects endogenous levels of GAK protein.
Observed Molecular Weight
144
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:5000; Not yet tested in other applications.
Other Product Names
GAK; Cyclin-G-associated kinase
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/O14976
Isotype
Rabbit IgG

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