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FOP Polyclonal Antibody

CAT: 0749-ABP51359-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP51359-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
FGFR1OP encodes a largely hydrophilic centrosomal protein, FGFR1 oncogene partner, that is required for anchoring microtubules to subcellular structures. A t (6;8) (q27; p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. Alterations in this gene may also be associated with Crohn's disease, Graves' disease, and vitiligo. Alternatively spliced transcript variants that encode different proteins have been identified.
Description
Rabbit Anti-FOP Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
FGFR1OP; FOP; FGFR1 oncogene partner
Gene ID
11116
Accession Number
O95684
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the C-terminal region of human FOP at AA range: 310-390
Clonality
Polyclonal
Tag
FGFR1 oncogene partner
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
43kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
FOP Polyclonal Antibody detects endogenous levels of FOP protein.
Observed Molecular Weight
43
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications.
Other Product Names
FGFR1OP; FOP; FGFR1 oncogene partner
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/O95684
Isotype
Rabbit IgG

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