EOMES Polyclonal Antibody

• Background:

  EOMES belongs to the TBR1 (T-box brain protein 1) sub-family of T-box genes that share the common DNA-binding T-box domain. The encoded protein (eomesodermin) is a transcription factor which is crucial for embryonic development of mesoderm and the central nervous system in vertebrates. The protein may also be necessary for the differentiation of effector CD8+ T cells which are involved in defense against viral infections. A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation. Alternative splicing results in multiple transcript variants.

• Description:

  Rabbit Anti-EOMES Polyclonal Antibody

• Product Name Alternative:

  EOMES; TBR2; Eomesodermin homolog; T-box brain protein 2; T-brain-2; TBR-2

• Gene ID:

  8320

• Accession Number:

  O95936

• Reactivity:

  Human, Mouse

• Immunogen:

  Synthesized peptide derived from the N-terminal region of human EOMES

• Clonality:

  Polyclonal

• Tag:

  Eomesodermin homolog

• Applications:

  WB, ELISA

• Purification Method:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration:

  1 mg/ml

• Molecular Weight:

  73kD

• Precautions:

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions:

  Gel pack with blue ice.

• Storage Conditions:

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes:

  EOMES Polyclonal Antibody detects endogenous levels of EOMES protein.

• Observed Molecular Weight:

  73

• Formulation:

  Liquid solution

• Buffer pH:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applications Notes:

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications.

• Other Product Names:

  EOMES; TBR2; Eomesodermin homolog; T-box brain protein 2; T-brain-2; TBR-2

• Tested Applications:

  WB, IHC, IF, IP, ELISA

• Host or Source:

  Rabbit

• Accession Number URL:

  http://www.uniprot.org/uniprot/O95936

• CAS Number:

  9007-83-4

• Isotype:

  Rabbit IgG