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Crk-L Polyclonal Antibody

CAT: 0749-ABP51054-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP51054-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CRKL encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.
Description
Rabbit Anti-Crk-L Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
CRKL; Crk-like protein
Gene ID
1399
Accession Number
P46109
Reactivity
Human, Mouse, Rat, Monkey
Immunogen
Synthesized peptide derived from human Crk-L around the non-phosphorylation site of Y207
Clonality
Polyclonal
Tag
Crk-like protein
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
39kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
Crk-L Polyclonal Antibody detects endogenous levels of Crk-L protein.
Observed Molecular Weight
39
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications.
Other Product Names
CRKL; Crk-like protein
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P46109
Isotype
Rabbit IgG

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