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Cofilin Polyclonal Antibody

CAT: 0749-ABP51019-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP51019-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CFL2 encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. Cofilin 2 is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in CFL2 cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants.
Description
Rabbit Anti-Cofilin Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
CFL1; CFL; Cofilin-1; 18 kDa phosphoprotein; p18; Cofilin; non-muscle isoform; CFL2; Cofilin-2; Cofilin, muscle isoform
Gene ID
1073/1072
Accession Number
P23528/Q9Y281
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the Internal region of human Cofilin at AA range: 30-110
Clonality
Polyclonal
Tag
Cofilin-1
Applications
WB, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
19kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
Cofilin Polyclonal Antibody detects endogenous levels of Cofilin protein.
Observed Molecular Weight
19
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:40000; Not yet tested in other applications.
Other Product Names
CFL1; CFL; Cofilin-1; 18 kDa phosphoprotein; p18; Cofilin; non-muscle isoform; CFL2; Cofilin-2; Cofilin, muscle isoform
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P23528
Isotype
Rabbit IgG

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