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CNPase Polyclonal Antibody

CAT: 0749-ABP51016-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP51016-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
2',3'-cyclic nucleotide-3'-phosphodiesterase (CNPase) is a membrane-bound enzyme that can link tubulin to membranes and may regulate cytoplasmic microtubule distribution. CNPase acts as a microtubule-associated protein by promoting microtubule assembly; this activity resides in the C-terminus of the enzyme. CNPase is firmly associated with tubulin from brain tissue and thyroid cells and can be found at high concentrations in central nervous system myelin and in the outer segments of photoreceptors in the retina. Acute lead intoxication leads to disturbances in CNPase activity and the morphology of myelin.
Description
Rabbit Anti-CNPase Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
CNP; 2'; 3'-cyclic-nucleotide 3'-phosphodiesterase; CNP; CNPase
Gene ID
1267
Accession Number
P09543
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the Internal region of human CNPase
Clonality
Polyclonal
Tag
2',3'-cyclic-nucleotide 3'-phosphodiesterase
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
47kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
CNPase Polyclonal Antibody detects endogenous levels of CNPase protein.
Observed Molecular Weight
47
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200
Other Product Names
CNP; 2'; 3'-cyclic-nucleotide 3'-phosphodiesterase; CNP; CNPase
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P09543
Isotype
Rabbit IgG

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