CDC46 Polyclonal Antibody

• Background :

  Minichromosome maintenance complex component 5 encoded by MCM5 is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation.

• Description :

  Rabbit Anti-CDC46 Polyclonal Antibody

• Product Name Alternative :

  MCM5; CDC46; DNA replication licensing factor MCM5; CDC46 homolog; P1-CDC46

• Gene ID :

  4174

• Accession Number :

  P33992

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Synthesized peptide derived from the N-terminal region of human CDC46 at AA range: 40-120

• Clonality :

  Polyclonal

• Tag :

  DNA replication licensing factor MCM5

• Applications :

  WB, IHC, IF, ELISA

• Purification Method :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Molecular Weight :

  90kD

• Precautions :

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions :

  Gel pack with blue ice.

• Storage Conditions :

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes :

  CDC46 Polyclonal Antibody detects endogenous levels of CDC46 protein.

• Observed Molecular Weight :

  90

• Formulation :

  Liquid solution

• Buffer pH :

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applications Notes :

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications.

• Other Product Names :

  MCM5; CDC46; DNA replication licensing factor MCM5; CDC46 homolog; P1-CDC46

• Tested Applications :

  WB, IHC, IF, IP, ELISA

• Host or Source :

  Rabbit

• Accession Number URL :

  http://www.uniprot.org/uniprot/P33992

• CAS Number :

  9007-83-4

• Isotype :

  Rabbit IgG