C/EBP ζ Polyclonal Antibody

• Background:

  CEBPZ belongs to the CEBP family. The encoded protein (CCAAT/enhancer binding protein zeta) plays a role in cellular response to environmental stimuli through a transcriptional process that involves heat shock factors, conserved DNA elements (heat shock elements or HSEs) and CCAAT boxes. The protein acts as a DNA-binding transcriptional activator and regulates the heat-shock protein 70 (HSP70) promoter in a CCAAT-dependent manner. The protein is also involved in cell growth and differentiation, particularly, hematopoietic differentiation. Methylation of the promoter of CEBPZ or mutations within CEBPZ may be correlated with occurance of acute myeloid leukemia (AML) .

• Description:

  Rabbit Anti-C/EBP ζ Polyclonal Antibody

• Product Name Alternative:

  CEBPZ; CBF2; CCAAT/enhancer-binding protein zeta; CCAAT-box-binding transcription factor; CBF; CCAAT-binding factor

• Gene ID:

  10153

• Accession Number:

  Q03701

• Reactivity:

  Human, Mouse

• Immunogen:

  Synthesized peptide derived from the N-terminal region of human C/EBP ζ at AA range: 10-90

• Clonality:

  Polyclonal

• Tag:

  CCAAT

• Applications:

  WB, IHC, IF, ELISA

• Purification Method:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration:

  1 mg/ml

• Molecular Weight:

  120kD

• Precautions:

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions:

  Gel pack with blue ice.

• Storage Conditions:

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes:

  C/EBP ζ Polyclonal Antibody detects endogenous levels of C/EBP ζ protein.

• Observed Molecular Weight:

  120

• Formulation:

  Liquid solution

• Buffer pH:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applications Notes:

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications.

• Other Product Names:

  CEBPZ; CBF2; CCAAT/enhancer-binding protein zeta; CCAAT-box-binding transcription factor; CBF; CCAAT-binding factor

• Tested Applications:

  WB, IHC, IF, IP, ELISA

• Host or Source:

  Rabbit

• Accession Number URL:

  http://www.uniprot.org/uniprot/Q03701

• CAS Number:

  9007-83-4

• Isotype:

  Rabbit IgG