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BubR1 Polyclonal Antibody

CAT: 0749-ABP50802-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP50802-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
BUB1B encodes a kinase involved in spindle checkpoint function. The protein (BUB1 mitotic checkpoint serine/threonine kinase B) has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.
Description
Rabbit Anti-BubR1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
BUB1B; BUBR1; MAD3L; SSK1; Mitotic checkpoint serine/threonine-protein kinase BUB1 beta; MAD3/BUB1-related protein kinase; hBUBR1; Mitotic checkpoint kinase MAD3L; Protein SSK1
Gene ID
701
Accession Number
O60566
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from the Internal region of human BubR1 at AA range: 310-390
Clonality
Polyclonal
Tag
Mitotic checkpoint serine threonine-protein kinase BUB1 beta
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
130kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
BubR1 Polyclonal Antibody detects endogenous levels of BubR1 protein.
Observed Molecular Weight
130
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:20000; Not yet tested in other applications.
Other Product Names
BUB1B; BUBR1; MAD3L; SSK1; Mitotic checkpoint serine/threonine-protein kinase BUB1 beta; MAD3/BUB1-related protein kinase; hBUBR1; Mitotic checkpoint kinase MAD3L; Protein SSK1
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/O60566
Isotype
Rabbit IgG

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