APBA2BP Polyclonal Antibody

• Background :

  The protein encoded by NECAB3 interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein (N-terminal EF-hand calcium binding protein 3), together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for NECAB3.

• Description :

  Rabbit Anti-APBA2BP Polyclonal Antibody

• Product Name Alternative :

  NECAB3; APBA2BP; NIP1; SYTIP2; XB51; N-terminal EF-hand calcium-binding protein 3; Amyloid beta A4 protein-binding family A member 2-binding protein; Nek2-interacting protein 1; Neuronal calcium-binding protein 3; X11L-binding protein 51

• Gene ID :

  63941

• Accession Number :

  Q96P71

• Reactivity :

  Human, Mouse

• Immunogen :

  Synthesized peptide derived from the C-terminal region of human APBA2BP at AA range: 290-370

• Clonality :

  Polyclonal

• Tag :

  N-terminal EF-hand calcium-binding protein 3

• Applications :

  WB, IHC, IF, ELISA

• Purification Method :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Molecular Weight :

  44kD

• Precautions :

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions :

  Gel pack with blue ice.

• Storage Conditions :

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes :

  APBA2BP Polyclonal Antibody detects endogenous levels of APBA2BP protein.

• Formulation :

  Liquid solution

• Buffer pH :

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applications Notes :

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:40000; Not yet tested in other applications.

• Other Product Names :

  NECAB3; APBA2BP; NIP1; SYTIP2; XB51; N-terminal EF-hand calcium-binding protein 3; Amyloid beta A4 protein-binding family A member 2-binding protein; Nek2-interacting protein 1; Neuronal calcium-binding protein 3; X11L-binding protein 51

• Tested Applications :

  WB, IHC, IF, IP, ELISA

• Host or Source :

  Rabbit

• Accession Number URL :

  http://www.uniprot.org/uniprot/Q96P71

• CAS Number :

  9007-83-4

• Isotype :

  Rabbit IgG