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CD41 Monoclonal Antibody

CAT: 0749-ABM40106-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABM40106-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ITGA2B encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. Integrin subunit alpha 2b plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in ITGA2B are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia.
Description
Mouse Anti-CD41 Monoclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
ITGA2B; GP2B; ITGAB; Integrin alpha-IIb; GPalpha IIb; GPIIb; Platelet membrane glycoprotein IIb; CD41
Gene ID
3674
Accession Number
P08514
Reactivity
Human
Immunogen
Synthetic Peptide
Clonality
Monoclonal
Tag
Integrin alpha-IIb
Applications
IHC, IF
Purification Method
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous human CD41/ Intergrin α2b protein.
Formulation
Liquid solution
Buffer pH
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100; IF 1:50-200
Other Product Names
ITGA2B; GP2B; ITGAB; Integrin alpha-IIb; GPalpha IIb; GPIIb; Platelet membrane glycoprotein IIb; CD41
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Mouse
Accession Number URL
http://www.uniprot.org/uniprot/P08514
Isotype
Mouse IgG1

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