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LRIG1 rabbit pAb

CAT: 0855-ES11850-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES11850-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Domain:The LRRs and the Ig-domains are each sufficient for EGFR/ERBB1 binding. This interaction is abolished only when these two domains are deleted., function:Act as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation., induction:By EGF., similarity:Contains 17 LRR (leucine-rich) repeats., similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains., subunit:Interacts with EGFR/ERBB1, ERBB2, ERBB3 and ERBB4., tissue specificity:Widely expressed.
Description
Domain: The LRRs and the Ig-domains are each sufficient for EGFR/ERBB1 binding. This interaction is abolished only when these two domains are deleted. function: Act as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation. induction: By EGF. similarity: Contains 17 LRR (leucine-rich) repeats. similarity: Contains 3 Ig-like C2-type (immunoglobulin-like) domains. subunit: Interacts with EGFR/ERBB1, ERBB2, ERBB3 and ERBB4. tissue specificity: Widely expressed.
UniProt
Q96JA1
Swiss Prot
Q96JA1
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Target
LRIG1
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
-20°C/1 year
Molecular Weight
120kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
120kD
Fragment
IgG
Subcellular Location
Cell membrane ; Single-pass type I membrane protein .
Gene ID (Human)
26018

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