COPB rabbit pAb

CAT: 0855-ES11764-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES11764-01Size:50 µL
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Background
This gene encodes a protein subunit of the coatomer complex associated with non-clathrin coated vesicles. The coatomer complex, also known as the coat protein complex 1, forms in the cytoplasm and is recruited to the Golgi by activated guanosine triphosphatases. Once at the Golgi membrane, the coatomer complex may assist in the movement of protein and lipid components back to the endoplasmic reticulum. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009]
Description
This gene encodes a protein subunit of the coatomer complex associated with non-clathrin coated vesicles. The coatomer complex, also known as the coat protein complex 1, forms in the cytoplasm and is recruited to the Golgi by activated guanosine triphosphatases. Once at the Golgi membrane, the coatomer complex may assist in the movement of protein and lipid components back to the endoplasmic reticulum. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009],
UniProt
P53618
Swiss Prot
P53618
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from part region of human protein AA range: 865-915
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
104kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
104kD
Fragment
IgG
Subcellular Location
Cytoplasm. Golgi apparatus membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein ; Cytoplasmic side . Cell membrane . Endoplasmic reticulum-Golgi intermediate compartment . The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it (By similarity) . Proteolytic cleavage by CAPN8 triggers translocation from Golgi to cytoplasm (By similarity) . Found in perinuclear vesicular-tubular clusters (VTCs) and in the Golgi region where associated with vesicles, buds and rims of the Golgi stack (By similarity) . Occasionally present at the trans-side of Golgi, but mainly present at the cis-Golgi side in transitional areas (TA), on so-called periph
Gene ID (Human)
1315

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