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ERR1 rabbit pAb

CAT: 0855-ES11349-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0855-ES11349-02Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a nuclear receptor that is closely related to the estrogen receptor. This protein acts as a site-specific transcription regulator and has been also shown to interact with estrogen and the transcripton factor TFIIB by direct protein-protein contact. The binding and regulatory activities of this protein have been demonstrated in the regulation of a variety of genes including lactoferrin, osteopontin, medium-chain acyl coenzyme A dehydrogenase (MCAD) and thyroid hormone receptor genes. A processed pseudogene of ESRRA is located on chromosome 13q12.1. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2013]
Description
The protein encoded by this gene is a nuclear receptor that is closely related to the estrogen receptor. This protein acts as a site-specific transcription regulator and has been also shown to interact with estrogen and the transcripton factor TFIIB by direct protein-protein contact. The binding and regulatory activities of this protein have been demonstrated in the regulation of a variety of genes including lactoferrin, osteopontin, medium-chain acyl coenzyme A dehydrogenase (MCAD) and thyroid hormone receptor genes. A processed pseudogene of ESRRA is located on chromosome 13q12. 1. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2013],
UniProt
P11474
Swiss Prot
P11474
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 160-240
Target
ERR1
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
-20°C/1 year
Molecular Weight
46kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
46kD
Fragment
IgG
Subcellular Location
Nucleus . Cytoplasm . Co-localizes to the cytoplasm only in presence of MAPK15. .
Gene ID (Human)
2101

UniProtKB · P11474

Steroid hormone receptor ERR1

ERR1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P11474
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ESRRA
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q14514
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmNucleus

Molecular function

DNA-bindingReceptor

Ligand

Metal-bindingZinc

Biological process

TranscriptionTranscription regulation

Domain

Zinc-finger

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