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WASL rabbit pAb

CAT: 0855-ES11262-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES11262-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the Wiskott-Aldrich syndrome (WAS) protein family. Wiskott-Aldrich syndrome proteins share similar domain structure, and associate with a variety of signaling molecules to alter the actin cytoskeleton. The encoded protein is highly expressed in neural tissues, and interacts with several proteins involved in cytoskeletal organization, including cell division control protein 42 (CDC42) and the actin-related protein-2/3 (ARP2/3) complex. The encoded protein may be involved in the formation of long actin microspikes, and in neurite extension. [provided by RefSeq, Jul 2013]
Description
This gene encodes a member of the Wiskott-Aldrich syndrome (WAS) protein family. Wiskott-Aldrich syndrome proteins share similar domain structure, and associate with a variety of signaling molecules to alter the actin cytoskeleton. The encoded protein is highly expressed in neural tissues, and interacts with several proteins involved in cytoskeletal organization, including cell division control protein 42 (CDC42) and the actin-related protein-2/3 (ARP2/3) complex. The encoded protein may be involved in the formation of long actin microspikes, and in neurite extension. [provided by RefSeq, Jul 2013],
UniProt
O00401
Swiss Prot
O00401
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 190-270
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
55kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
55kD
Fragment
IgG
Subcellular Location
Cytoplasm, cytoskeleton . Nucleus . Cytoplasm . Preferentially localized in the cytoplasm when phosphorylated and in the nucleus when unphosphorylated (By similarity) . Exported from the nucleus by an nuclear export signal (NES) -dependent mechanism to the cytoplasm (By similarity) . .
Gene ID (Human)
8976

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