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LAP2A rabbit pAb

CAT: 0855-ES10927-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0855-ES10927-02Size:100 µL
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Background
Thymopoietin encoded by TMPO resides in the nucleus and may play a role in the assembly of the nuclear lamina, and thus help maintain the structural organization of the nuclear envelope. It may function as a receptor for the attachment of lamin filaments to the inner nuclear membrane. Mutations in this gene are associated with dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Description
Thymopoietin encoded by TMPO resides in the nucleus and may play a role in the assembly of the nuclear lamina, and thus help maintain the structural organization of the nuclear envelope. It may function as a receptor for the attachment of lamin filaments to the inner nuclear membrane. Mutations in this gene are associated with dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
UniProt
P42166
Swiss Prot
P42166
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
76kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
76kD
Fragment
IgG
Subcellular Location
Nucleus. Chromosome. Expressed diffusely throughout the nucleus.
Gene ID (Human)
7112

UniProtKB · P42166

Lamina-associated polypeptide 2, isoform alpha

LAP2A_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P42166
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
TMPO
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
P08918, P08919, Q14860, Q16295
Protein keywords

Technical term

3D-structureDirect protein sequencingPharmaceuticalProteomics identificationReference proteome

PTM

AcetylationMethylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Disease

Cardiomyopathy

Cellular component

ChromosomeNucleus

Domain

Coiled coil

Molecular function

DNA-binding

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