PSD4 rabbit pAb

CAT: 0855-ES10877-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES10877-01Size:50 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Function:Guanine nucleotide exchange factor for ARF6-like protein. Involved in membrane recycling., similarity:Contains 1 PH domain., similarity:Contains 1 SEC7 domain., subcellular location:Accumulates in dynamic actin-rich membrane ruffles and microvilli-like structures., tissue specificity:Widely expressed. Highest levels of expression are found in placenta, pancreas, spleen, thymus and peripheral blood.
Description
Function: Guanine nucleotide exchange factor for ARF6-like protein. Involved in membrane recycling. similarity: Contains 1 PH domain. similarity: Contains 1 SEC7 domain. subcellular location: Accumulates in dynamic actin-rich membrane ruffles and microvilli-like structures. tissue specificity: Widely expressed. Highest levels of expression are found in placenta, pancreas, spleen, thymus and peripheral blood.
UniProt
Q8NDX1
Swiss Prot
Q8NDX1
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
116kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
116kD
Fragment
IgG
Subcellular Location
Cell membrane . Cell projection, ruffle membrane . In interphase associated with the plasma membrane, in particular with membrane ruffling regions (PubMed:23603394) . Accumulates in dynamic actin-rich membrane ruffles and microvilli-like structures (PubMed:12082148) . Recruited to membranes via phosphatidylinositol phosphate-binding (Probable) . .
Gene ID (Human)
23550

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