PSD4 rabbit pAb

• Background:

  Function:Guanine nucleotide exchange factor for ARF6-like protein. Involved in membrane recycling., similarity:Contains 1 PH domain., similarity:Contains 1 SEC7 domain., subcellular location:Accumulates in dynamic actin-rich membrane ruffles and microvilli-like structures., tissue specificity:Widely expressed. Highest levels of expression are found in placenta, pancreas, spleen, thymus and peripheral blood.

• Description:

  Function: Guanine nucleotide exchange factor for ARF6-like protein. Involved in membrane recycling. similarity: Contains 1 PH domain. similarity: Contains 1 SEC7 domain. subcellular location: Accumulates in dynamic actin-rich membrane ruffles and microvilli-like structures. tissue specificity: Widely expressed. Highest levels of expression are found in placenta, pancreas, spleen, thymus and peripheral blood.

• UniProt:

  Q8NDX1

• Swiss Prot:

  Q8NDX1

• Reactivity:

  Human; Rat; Mouse

• Immunogen:

  Synthesized peptide derived from part region of human protein

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  WB 1:500-2000 ELISA 1:5000-20000

• Molecular Weight:

  116kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  116kD

• Fragment:

  IgG

• Subcellular Location:

  Cell membrane . Cell projection, ruffle membrane . In interphase associated with the plasma membrane, in particular with membrane ruffling regions (PubMed:23603394) . Accumulates in dynamic actin-rich membrane ruffles and microvilli-like structures (PubMed:12082148) . Recruited to membranes via phosphatidylinositol phosphate-binding (Probable) . .

• Gene ID (Human):

  23550