PSD4 rabbit pAb

• Background :

  Function:Guanine nucleotide exchange factor for ARF6-like protein. Involved in membrane recycling., similarity:Contains 1 PH domain., similarity:Contains 1 SEC7 domain., subcellular location:Accumulates in dynamic actin-rich membrane ruffles and microvilli-like structures., tissue specificity:Widely expressed. Highest levels of expression are found in placenta, pancreas, spleen, thymus and peripheral blood.

• Description :

  Function: Guanine nucleotide exchange factor for ARF6-like protein. Involved in membrane recycling. similarity: Contains 1 PH domain. similarity: Contains 1 SEC7 domain. subcellular location: Accumulates in dynamic actin-rich membrane ruffles and microvilli-like structures. tissue specificity: Widely expressed. Highest levels of expression are found in placenta, pancreas, spleen, thymus and peripheral blood.

• UniProt :

  Q8NDX1

• Swiss Prot :

  Q8NDX1

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  Synthesized peptide derived from part region of human protein

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000 ELISA 1:5000-20000

• Molecular Weight :

  116kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  116kD

• Fragment :

  IgG

• Subcellular Location :

  Cell membrane . Cell projection, ruffle membrane . In interphase associated with the plasma membrane, in particular with membrane ruffling regions (PubMed:23603394) . Accumulates in dynamic actin-rich membrane ruffles and microvilli-like structures (PubMed:12082148) . Recruited to membranes via phosphatidylinositol phosphate-binding (Probable) . .

• Gene ID (Human) :

  23550