NRBP rabbit pAb
CAT:
855-ES10837-01
Size:
50 μL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
NRBP rabbit pAb
- Description: Caution: Author states that kinase activity observed in PubMed: 11956649 may be due to sample contamination. This protein is predicted to be catalytically inactive. Domain: The protein kinase domain is predicted to be catalytically inactive. function: May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases. Binding to the NS3 protein of dengue virus type 2 appears to subvert this activity into the alteration of the intracellular membrane structure associated with flaviviral replication. similarity: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. similarity: Contains 1 protein kinase domain. subcellular location: Colocalizes with activated RAC3 to endomembranes and at the cell periphery in lamellipodia. subunit: Homodimer. Binds to MLF1, recruiting a serine kinase which phosphorylates both itself and MLF1. Phosphorylated MLF1 binds to YWHAZ and is retained in the cytoplasm. tissue specificity: Ubiquitously expressed in all tissues examined with high levels in the testis.
- Gene ID: 29959
- UniProt: Q9UHY1
- Cellular Locus: Cytoplasm, cell cortex. Endomembrane system. Cell projection, lamellipodium. Colocalizes with activated RAC3 to endomembranes and at the cell periphery in lamellipodia.
- Host: Rabbit
- Species Reactivity: Human, Mouse
- Immunogen: Synthesized peptide derived from part region of human protein
- Clonality: Polyclonal
- Validated Applications: WB, ELISA
- Stability: 1 year
- Concentration: 1 mg/mL
- Dilution: WB 1:500-2000 ELISA 1:5000-20000
- Molecular Weight: 58kD
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.