Products for Research Use Only
RegisterLogin

MCM8 rabbit pAb

CAT: 0855-ES10748-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0855-ES10748-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the mini-chromosome maintenance proteins is a key component of the pre-replication complex and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the mini-chromosome maintenance proteins. The encoded protein may interact with other mini-chromosome maintenance proteins and play a role in DNA replication. This gene may be associated with length of reproductive lifespan and menopause. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2013]
Description
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the mini-chromosome maintenance proteins is a key component of the pre-replication complex and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the mini-chromosome maintenance proteins. The encoded protein may interact with other mini-chromosome maintenance proteins and play a role in DNA replication. This gene may be associated with length of reproductive lifespan and menopause. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2013],
UniProt
Q9UJA3
Swiss Prot
Q9UJA3
Reactivity
Human; Rat
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
92kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
92kD
Fragment
IgG
Subcellular Location
Nucleus . Chromosome . Localizes to nuclear foci (PubMed:26215093) . Localizes to double-stranded DNA breaks (PubMed:23401855) . Binds chromatin throughout the cell cycle (PubMed:15684404) . .
Gene ID (Human)
84515

Related Products

CatalogName
ES6208-01MCM4 rabbit pAb
ES3947-01MCM3 rabbit pAb
ES4101-01MCM7 rabbit pAb
ES4184-01MCM6 rabbit pAb
ES10749-01MCM9 rabbit pAb
ES6207-01MCM4 (phospho Ser54) rabbit pAb
ES14999-01MCM2 (phospho-Ser139) rabbit pAb
ES14996-01MCM3 (phospho-Ser112) rabbit pAb
ES4666-01RAB3IP rabbit pAb
ES20751-01Gab1 Rabbit rabbit pAb

Alternative Products

CatalogName
GTR18607606-01MCM8 Rabbit pAb
TA378406MCM8 Rabbit Polyclonal Antibody
NBP1-58129Rabbit Polyclonal MCM8 Antibody
GB114306-100Anti-MCM8 Rabbit pAb
MBS4508741-01Rabbit anti-MCM8 Antibody
MBS8561208-01MCM8
abx457397-01DNA Helicase MCM8 (MCM8) Antibody

Popular Products