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BIN2 rabbit pAb

CAT: 0855-ES10664-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0855-ES10664-02Size:100 µL
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Background
Induction:Up-regulated during monocytic differentiation., similarity:Contains 1 BAR domain., subunit:Interacts with BIN1., tissue specificity:Highest level expression seen in spleen and peripheral blood leukocytes and is also expressed at high levels in thymus, colon and placenta, suggesting preferential expression in hematopoietic tissues.
Description
Induction: Up-regulated during monocytic differentiation. similarity: Contains 1 BAR domain. subunit: Interacts with BIN1. tissue specificity: Highest level expression seen in spleen and peripheral blood leukocytes and is also expressed at high levels in thymus, colon and placenta, suggesting preferential expression in hematopoietic tissues.
UniProt
Q9UBW5
Swiss Prot
Q9UBW5
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 260-340
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
62kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
62kD
Fragment
IgG
Subcellular Location
Cytoplasm . Cell projection, podosome membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasm, cell cortex . Cell projection, phagocytic cup . Associates with membranes enriched in phosphoinositides. Detected in the actin-rich cell cortex at the leading edge of migrating cells. Detected at podosomes, at an actin-rich ring-like structure. .
Gene ID (Human)
51411

UniProtKB · Q9UBW5

Bridging integrator 2

BIN2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9UBW5
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
BIN2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B7Z6F3, F5H0W4, Q86VV0, Q9NWK4, Q9UKN4
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell junctionCell membraneCell projectionCytoplasmMembrane

Domain

Coiled coil

PTM

Phosphoprotein

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