KDM4D rabbit pAb

• Background:

  Caution:It is uncertain whether Met-1 or Met-4 is the initiator., cofactor:Binds 1 Fe (2+) ion per subunit., function:Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys-9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate., similarity:Belongs to the JHDM3 histone demethylase family., similarity:Contains 1 JmjC domain., similarity:Contains 1 JmjN domain.

• Description:

  Caution: It is uncertain whether Met-1 or Met-4 is the initiator. Cofactor: Binds 1 Fe (2+) ion per subunit. function: Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys-9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. similarity: Belongs to the JHDM3 histone demethylase family. similarity: Contains 1 JmjC domain. similarity: Contains 1 JmjN domain.

• UniProt:

  Q6B0I6

• Swiss Prot:

  Q6B0I6

• Reactivity:

  Human; Rat; Mouse

• Immunogen:

  Synthesized peptide derived from human protein . at AA range: 400-480

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  WB 1:500-2000 ELISA 1:5000-20000

• Molecular Weight:

  57kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  57kD

• Fragment:

  IgG

• Subcellular Location:

  Nucleus .

• Gene ID (Human):

  55693