UBAP1 rabbit pAb

CAT: 0855-ES10430-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES10430-01Size:50 µL
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Background
This gene is a member of the UBA domain family, whose members include proteins having connections to ubiquitin and the ubiquitination pathway. The ubiquitin associated domain is thought to be a non-covalent ubiquitin binding domain consisting of a compact three helix bundle. This particular protein originates from a gene locus in a refined region on chromosome 9 undergoing loss of heterozygosity in nasopharyngeal carcinoma (NPC) . Taking into account its cytogenetic location, this UBA domain family member is being studies as a putative target for mutation in nasopharyngeal carcinomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
Description
This gene is a member of the UBA domain family, whose members include proteins having connections to ubiquitin and the ubiquitination pathway. The ubiquitin associated domain is thought to be a non-covalent ubiquitin binding domain consisting of a compact three helix bundle. This particular protein originates from a gene locus in a refined region on chromosome 9 undergoing loss of heterozygosity in nasopharyngeal carcinoma (NPC). Taking into account its cytogenetic location, this UBA domain family member is being studies as a putative target for mutation in nasopharyngeal carcinomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010],
UniProt
Q9NZ09
Swiss Prot
Q9NZ09
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
55kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
55kD
Fragment
IgG
Subcellular Location
Cytoplasm, cytosol . Endosome . Predominantly cytosolic (PubMed:21757351) . Recruited to endosomes as part of the ESCRT-I complex (PubMed:21757351) . .
Gene ID (Human)
51271

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