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TM1L1 rabbit pAb

CAT: 0855-ES10360-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES10360-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Function:Probable adapter protein involved in signaling pathways. Interacts with the SH2 and SH3 domains of various signaling proteins when it is phosphorylated. May promotes FYN activation, possibly by disrupting intramolecular SH3-dependent interactions., PTM:Phosphorylated on tyrosines by FYN (By similarity) . Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the TOM1 family., similarity:Contains 1 GAT domain., similarity:Contains 1 VHS domain., subunit:Interacts with FYN, GRB2 and PIK3R1 when phosphorylated.
Description
Function: Probable adapter protein involved in signaling pathways. Interacts with the SH2 and SH3 domains of various signaling proteins when it is phosphorylated. May promotes FYN activation, possibly by disrupting intramolecular SH3-dependent interactions. PTM: Phosphorylated on tyrosines by FYN (By similarity). Phosphorylated upon DNA damage, probably by ATM or ATR. similarity: Belongs to the TOM1 family. similarity: Contains 1 GAT domain. similarity: Contains 1 VHS domain. subunit: Interacts with FYN, GRB2 and PIK3R1 when phosphorylated.
UniProt
O75674
Swiss Prot
O75674
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
52kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
52kD
Fragment
IgG
Subcellular Location
Golgi apparatus, Golgi stack. Endosome membrane . Cytoplasm . Membrane ; Peripheral membrane protein ; Cytoplasmic side . A small proportion is membrane-associated. .
Gene ID (Human)
10040

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