RegisterLogin

ABCA4 rabbit pAb

CAT: 0855-ES10155-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES10155-01Size:50 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White) . This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is a retina-specific ABC transporter with N-retinylidene-PE as a substrate. It is expressed exclusively in retina photoreceptor cells, indicating the gene product mediates transport of an essental molecule across the photoreceptor cell membrane. Mutations in this gene are found in patients diagnosed with Stargardt disease, a form of juvenile-onset macular degeneration. Mutations in this gene are
Description
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is a retina-specific ABC transporter with N-retinylidene-PE as a substrate. It is expressed exclusively in retina photoreceptor cells, indicating the gene product mediates transport of an essental molecule across the photoreceptor cell membrane. Mutations in this gene are found in patients diagnosed with Stargardt disease, a form of juvenile-onset macular degeneration. Mutations in this gene are
UniProt
P78363
Swiss Prot
P78363
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 630-710
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
250kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
250kD
Fragment
IgG
Subcellular Location
Membrane ; Multi-pass membrane protein . Endoplasmic reticulum . Cytoplasmic vesicle . Cell projection, cilium, photoreceptor outer segment . Localized to the rim and incisures of rod outer segments disks. .
Gene ID (Human)
24

Related Products

CatalogName
ES1561-01ABCA6 rabbit pAb
ES1567-01ABCD4 rabbit pAb
ES1562-01ABCA8 rabbit pAb
ES9420-01ABCA5 rabbit pAb
ES9427-01ABCG4 rabbit pAb
ES9422-01ABCA9 rabbit pAb
ES18515-01ABCAB rabbit pAb
ES9421-01ABCA7 rabbit pAb
ES9419-01ABCA3 rabbit pAb
ES9418-01ABCAC rabbit pAb

Alternative Products

CatalogName
E47R11356ABCA4 Rabbit pAb
MBS9513210-01ABCA4 Rabbit Polyclonal Antibody
YLD0049-01Rabbit anti-ABCA4 Antibody
NBP3-17333-25ulRabbit Polyclonal ABCA4 Antibody
GB113104Anti-ABCA4 Rabbit pAb
APR18171N-01ABCA4 Rabbit pAb (APR18171N)
519664-01ABCA4

Popular Products