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ABCA8 rabbit pAb

CAT: 0855-ES1562-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES1562-01Size:50 µL
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Background
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White) . This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. The encoded protein may regulate lipid metabolism and be involved in the formation and maintenance of myelin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Description
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. The encoded protein may regulate lipid metabolism and be involved in the formation and maintenance of myelin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014],
Product Name Alternative
ABCA8; KIAA0822; ATP-binding cassette sub-family A member 8
UniProt
O94911
Swiss Prot
O94911
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human ABCA8. AA range:1151-1200
Target
ABCA8
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
179kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
179kD
Fragment
IgG
Subcellular Location
Cell membrane ; Multi-pass membrane protein . Basolateral cell membrane . Predominantly expressed on the sinusoidal plasma membrane. .
Other Product Names
ABCA8; KIAA0822; ATP-binding cassette sub-family A member 8
Gene ID (Human)
10351

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