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RELN rabbit pAb

CAT: 0855-ES10146-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES10146-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a large secreted extracellular matrix protein thought to control cell-cell interactions critical for cell positioning and neuronal migration during brain development. This protein may be involved in schizophrenia, autism, bipolar disorder, major depression and in migration defects associated with temporal lobe epilepsy. Mutations of this gene are associated with autosomal recessive lissencephaly with cerebellar hypoplasia. Two transcript variants encoding distinct isoforms have been identified for this gene. Other transcript variants have been described but their full length nature has not been determined. [provided by RefSeq, Jul 2008]
Description
This gene encodes a large secreted extracellular matrix protein thought to control cell-cell interactions critical for cell positioning and neuronal migration during brain development. This protein may be involved in schizophrenia, autism, bipolar disorder, major depression and in migration defects associated with temporal lobe epilepsy. Mutations of this gene are associated with autosomal recessive lissencephaly with cerebellar hypoplasia. Two transcript variants encoding distinct isoforms have been identified for this gene. Other transcript variants have been described but their full length nature has not been determined. [provided by RefSeq, Jul 2008],
UniProt
P78509
Swiss Prot
P78509
Reactivity
Human; Rat
Immunogen
Synthesized peptide derived from human protein . at AA range: 270-350
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF
Concentration
1 mg/ml
Dilution
IHC-p 1:50-300
Molecular Weight
380kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
380kD
Fragment
IgG
Subcellular Location
Secreted, extracellular space, extracellular matrix .
Gene ID (Human)
5649

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