R51A1 rabbit pAb

• Background:

  Alternative products:Additional isoforms seem to exist, function:May participate in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Binds to single and double stranded DNA, and is capable of aggregating DNA. Also binds RNA., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., subcellular location:Colocalizes with RAD51 to multiple nuclear foci., subunit:Isoform 2 interacts with RAD51., tissue specificity:Highly expressed in testis and thymus. Lower levels in colon and small intestine. Little or no expression in spleen, prostate, ovary and peripheral blood leukocytes.

• Description:

  Alternative products: Additional isoforms seem to exist, function: May participate in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Binds to single and double stranded DNA, and is capable of aggregating DNA. Also binds RNA. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. subcellular location: Colocalizes with RAD51 to multiple nuclear foci. subunit: Isoform 2 interacts with RAD51. tissue specificity: Highly expressed in testis and thymus. Lower levels in colon and small intestine. Little or no expression in spleen, prostate, ovary and peripheral blood leukocytes.

• Gene ID:

  10635

• UniProt:

  Q96B01

• Cellular Locus:

  Chromosome. Nucleus. Chromosome, telomere. Colocalizes with RAD51 to multiple nuclear foci (By similarity). Colocalizes with DMC1 on meiotic chromatin (By similarity)..

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse,

• Reactivity:

  Human; Mouse

• Immunogen:

  Synthesized peptide derived from human protein . at AA range: 90-170

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  WB, ELISA

• Validated Applications:

  WB, ELISA

• Stability:

  -20°C/1 year

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-2000 ELISA 1:5000-20000

• Molecular Weight:

  38kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  38 kD

• Subcellular Location:

  Chromosome . Nucleus . Chromosome, telomere . Colocalizes with RAD51 to multiple nuclear foci (By similarity) . Colocalizes with DMC1 on meiotic chromatin (By similarity) . .

• Gene ID (Human):

  10635

• SwissProt (Human):

  Q96B01