GNA13 rabbit pAb

CAT: 0855-ES9699-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES9699-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Function:Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems., PTM:Palmitoylation is critical for proper membrane localization and signaling., PTM:Phosphorylation on Thr-203 by PKA destabilizes the heterotrimer of alpha, beta and gamma, and inhibits Rho activation., similarity:Belongs to the G-alpha family. G (12) subfamily., subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV., subunit:G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Interacts with UBXD5.
Description
Function: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. PTM: Palmitoylation is critical for proper membrane localization and signaling. PTM: Phosphorylation on Thr-203 by PKA destabilizes the heterotrimer of alpha, beta and gamma, and inhibits Rho activation. similarity: Belongs to the G-alpha family. G (12) subfamily. subcellular location: Identified by mass spectrometry in melanosome fractions from stage I to stage IV. subunit: G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Interacts with UBXD5.
UniProt
Q14344
Swiss Prot
Q14344
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Target
GNA13
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
-20°C/1 year
Molecular Weight
41kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
41kD
Fragment
IgG
Subcellular Location
Cell membrane ; Lipid-anchor . Melanosome . Cytoplasm . Nucleus . Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065) . Detected in the cytoplasm of Leydig cells and in the seminiferous epithelium, including differentiating cells from the spermatogonia to mature spermatozoa stages (PubMed:18703424) . In round spermatids, also present in the nuclei (PubMed:18703424) . .
Gene ID (Human)
10672

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