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RGPA1 rabbit pAb

CAT: 0855-ES9686-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES9686-01Size:50 µL
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Background
This gene encodes a major subunit of the RAL-GTPase activating protein. A similar protein in mouse binds E12, a transcriptional regulator of immunoglobulin genes. The mouse protein also functions in skeletal muscle by binding to the regulatory 14-3-3 proteins upon stimulation with insulin or muscle contraction. A pseudogene of this gene has been identified on chromosome 9. [provided by RefSeq, Oct 2016]
Description
This gene encodes a major subunit of the RAL-GTPase activating protein. A similar protein in mouse binds E12, a transcriptional regulator of immunoglobulin genes. The mouse protein also functions in skeletal muscle by binding to the regulatory 14-3-3 proteins upon stimulation with insulin or muscle contraction. A pseudogene of this gene has been identified on chromosome 9. [provided by RefSeq, Oct 2016],
UniProt
Q6GYQ0
Swiss Prot
Q6GYQ0
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
223kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
223kD
Fragment
IgG
Subcellular Location
Cytoplasm . Nucleus . Translocated to the nucleus, when associated with TCF3/E12. .
Gene ID (Human)
253959

UniProtKB · Q6GYQ0

Ral GTPase-activating protein subunit alpha-1

RGPA1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q6GYQ0
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
RALGAPA1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A6NMA4, B9EK38, C5NU19, O94960, Q6GYP9, Q6ZT23, Q86YF3, Q86YF5, Q8ND69
Protein keywords

Coding sequence diversity

Alternative splicing

Domain

Coiled coil

Cellular component

CytoplasmNucleus

Disease

Disease variant

Molecular function

GTPase activation

PTM

Phosphoprotein

Technical term

Proteomics identificationReference proteome

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