CCDC8 rabbit pAb

• Background:

  This gene encodes a coiled-coil domain-containing protein. The encoded protein functions as a cofactor required for p53-mediated apoptosis following DNA damage, and may also play a role in growth through interactions with the cytoskeletal adaptor protein obscurin-like 1. Mutations in this gene are a cause of 3M syndrome-3 (3M3) . [provided by RefSeq, Dec 2011]

• Description:

  This gene encodes a coiled-coil domain-containing protein. The encoded protein functions as a cofactor required for p53-mediated apoptosis following DNA damage, and may also play a role in growth through interactions with the cytoskeletal adaptor protein obscurin-like 1. Mutations in this gene are a cause of 3M syndrome-3 (3M3). [provided by RefSeq, Dec 2011],

• UniProt:

  Q9H0W5

• Swiss Prot:

  Q9H0W5

• Reactivity:

  Human; Rat; Mouse

• Immunogen:

  Synthesized peptide derived from part region of human protein

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  WB 1:500-2000 ELISA 1:5000-20000

• Molecular Weight:

  59kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  59kD

• Fragment:

  IgG

• Subcellular Location:

  Cytoplasm . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome .

• Gene ID (Human):

  83987