CLD14 rabbit pAb

CAT: 0855-ES9547-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES9547-01Size:50 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. The encoded protein also binds specifically to the WW domain of Yes-associated protein. Defects in this gene are the cause of an autosomal recessive form of nonsyndromic sensorineural deafness. It is also reported that four synonymous variants in this gene are associated with kidney stones and reduced bone mineral density. Several
Description
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. The encoded protein also binds specifically to the WW domain of Yes-associated protein. Defects in this gene are the cause of an autosomal recessive form of nonsyndromic sensorineural deafness. It is also reported that four synonymous variants in this gene are associated with kidney stones and reduced bone mineral density. Several
UniProt
O95500
Swiss Prot
O95500
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Target
CLD14
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
-20°C/1 year
Molecular Weight
26kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
26kD
Fragment
IgG
Subcellular Location
Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.
Gene ID (Human)
23562

Related Products

CatalogName
ES19940-01CLD15 rabbit pAb
ES9546-01CLD12 rabbit pAb
ES17380-01CLD24 rabbit pAb
ES4666-01RAB3IP rabbit pAb
ES20751-01Gab1 Rabbit rabbit pAb
ES20703-01JAK2 Rabbit rabbit pAb
ES20758-01ERK1 Rabbit rabbit pAb
ES20599-01VEGF Rabbit rabbit pAb
ES20825-01ATG7 Rabbit rabbit pAb
ES20596-01WIPI2 Rabbit rabbit pAb

Alternative Products

CatalogName
E28PN0601CLD14 Rabbit Polyclonal Antibody
PAV897Rabbit Anti-CLD14/CLDN14 Polyclonal Antibody
C43146-01CLD14 Antibody
534807-01CLD14 discontinued
STJ190705Anti-CLD14 antibody
E11-200601CLD14 Polyclonal Antibody
A06550Anti-CLD14 CLDN14 Antibody
RTR015Rabbit-to-Rabbit Blocking Reagent
NBP1-71681Rabbit Normal Rabbit Serum
AR05252FC-NRabbit IgG Rabbit Protein

Popular Products