CHD9 rabbit pAb

• Background:

  Function:Acts as a transcriptional coactivator for PPARA and possibly other nuclear receptors. Proposed to be a ATP-dependent chromatin remodeling protein. Has DNA-dependent ATPase activity and binds to A/T-rich DNA. Associates with A/T-rich regulatory regions in promoters of genes that participate in the differentiation of progenitors during osteogenesis., PTM:Phosphorylated on serine and tyrosine residues., sequence caution:Wrong choice of frame., similarity:Belongs to the SNF2/RAD54 helicase family., similarity:Contains 1 helicase ATP-binding domain., similarity:Contains 1 helicase C-terminal domain., similarity:Contains 2 chromo domains., subunit:Interacts with PPARA. Probably interacts with ESR1 and NR1I3., tissue specificity:Widely expressed at low levels. In bone marrow, expression is restricted to osteoprogenitor cells adjacent to mature osteoblasts.

• Description:

  Function: Acts as a transcriptional coactivator for PPARA and possibly other nuclear receptors. Proposed to be a ATP-dependent chromatin remodeling protein. Has DNA-dependent ATPase activity and binds to A/T-rich DNA. Associates with A/T-rich regulatory regions in promoters of genes that participate in the differentiation of progenitors during osteogenesis. PTM: Phosphorylated on serine and tyrosine residues. sequence Caution: Wrong choice of frame. similarity: Belongs to the SNF2/RAD54 helicase family. similarity: Contains 1 helicase ATP-binding domain. similarity: Contains 1 helicase C-terminal domain. similarity: Contains 2 chromo domains. subunit: Interacts with PPARA. Probably interacts with ESR1 and NR1I3. tissue specificity: Widely expressed at low levels. In bone marrow, expression is restricted to osteoprogenitor cells adjacent to mature osteoblasts.

• UniProt:

  Q3L8U1

• Swiss Prot:

  Q3L8U1

• Reactivity:

  Human; Mouse

• Immunogen:

  Synthesized peptide derived from part region of human protein

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  IHC; IF

• Concentration:

  1 mg/ml

• Dilution:

  IHC-p 1:50-300

• Molecular Weight:

  318kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  318kD

• Fragment:

  IgG

• Subcellular Location:

  Cytoplasm . Nucleus .

• Gene ID (Human):

  80205