Products for Research Use Only
RegisterLogin

CAN6 rabbit pAb

CAT: 0855-ES9485-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0855-ES9485-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is highly expressed in the placenta. Its C-terminal region lacks any homology to the calmodulin-like domain of other calpains. The protein lacks critical active site residues and thus is suggested to be proteolytically inactive. The protein may play a role in tumor formation by inhibiting apoptosis and promoting angiogenesis. [provided by RefSeq, Nov 2009]
Description
Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is highly expressed in the placenta. Its C-terminal region lacks any homology to the calmodulin-like domain of other calpains. The protein lacks critical active site residues and thus is suggested to be proteolytically inactive. The protein may play a role in tumor formation by inhibiting apoptosis and promoting angiogenesis. [provided by RefSeq, Nov 2009],
UniProt
Q9Y6Q1
Swiss Prot
Q9Y6Q1
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
70kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
70kD
Fragment
IgG
Subcellular Location
Cytoplasm, perinuclear region . Cytoplasm, cytoskeleton, spindle . During mitose associated with the mitotic spindle. At telophase colocalized to the midbody spindle.
Gene ID (Human)
827

Related Products

CatalogName
ES11794-01CAN1 rabbit pAb
ES9486-01CAN7 rabbit pAb
ES9484-01CAN3 rabbit pAb
ES4666-01RAB3IP rabbit pAb
ES20751-01Gab1 Rabbit rabbit pAb
ES20703-01JAK2 Rabbit rabbit pAb
ES20758-01ERK1 Rabbit rabbit pAb
ES20830-01ATG14L Rabbit rabbit pAb
ES20829-01ATG4a Rabbit rabbit pAb
ES20658-01NM23A Rabbit rabbit pAb

Alternative Products

CatalogName
E28PN0539CAN6 Rabbit Polyclonal Antibody
PAV655Rabbit Anti-CAN6/CAPN6 Polyclonal Antibody
533969-01CAN6 discontinued
C42857-01CAN6 Antibody
BT-AP14647-01CAN6 Polyclonal Antibody
STJ190643Anti-CAN6 antibody
E101679Mouse CAN6 ELISA Kit
E101678Human CAN6 ELISA Kit
E101680Rat CAN6 ELISA Kit
WP0964-01U-Blot® CAN6 Polyclonal Antibody

Popular Products