AMOT rabbit pAb

CAT: 0855-ES9390-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES9390-01Size:50 µL
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Background
This gene belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Description
This gene belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
UniProt
Q4VCS5
Swiss Prot
Q4VCS5
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 710-790
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
119kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
119kD
Fragment
IgG
Subcellular Location
Cell junction, tight junction . Localized on the cell surface. May act as a transmembrane protein.
Gene ID (Human)
154796

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