AAT1 rabbit pAb

• Background :

  Alternative products:Additional isoforms (AAT-1L and AAT-1S) may exist, function:Isoform 4 may play a role in spermatogenesis., PTM:Isoform 4 is phosphorylated by PKA., subcellular location:Isoform 4 is found in the mitochondria and localized in the neck of the sperm., subunit:Interacts with AMY1 and AKAP1. Isoform 4 belongs to a complex together with AMY1, AKAP1 and PRKAR2B. Isoform 3 does not interact with AMY1., tissue specificity:Isoform 1 is strongly expressed in the liver. Isoform 4 is widely expressed, but strongly expressed in all spermatogenesis-related tissues, including the testis, the epithelium of cauda and the corpus epididymis. Isoform 4 is present in the spermatid and mature sperm. Isoform 4 is also expressed in Leydig cells. Isoform 3 is expressed in the testis.

• Description :

  Alternative products: Additional isoforms (AAT-1L and AAT-1S) may exist, function: Isoform 4 may play a role in spermatogenesis. PTM: Isoform 4 is phosphorylated by PKA. subcellular location: Isoform 4 is found in the mitochondria and localized in the neck of the sperm. subunit: Interacts with AMY1 and AKAP1. Isoform 4 belongs to a complex together with AMY1, AKAP1 and PRKAR2B. Isoform 3 does not interact with AMY1. tissue specificity: Isoform 1 is strongly expressed in the liver. Isoform 4 is widely expressed, but strongly expressed in all spermatogenesis-related tissues, including the testis, the epithelium of cauda and the corpus epididymis. Isoform 4 is present in the spermatid and mature sperm. Isoform 4 is also expressed in Leydig cells. Isoform 3 is expressed in the testis.

• UniProt :

  Q7Z4T9

• Swiss Prot :

  Q7Z4T9

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  Synthesized peptide derived from human protein . at AA range: 310-390

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000 ELISA 1:5000-20000

• Molecular Weight :

  66kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  66kD

• Fragment :

  IgG

• Subcellular Location :

  Mitochondrion . Cytoplasm . Cytoplasm, cytoskeleton, cilium axoneme . Localized in the neck of the sperm.; [Isoform 7]: Cytoplasm .

• Gene ID (Human) :

  89876