EDAR rabbit pAb

• Background:

  This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia. [provided by RefSeq, Jul 2008]

• Description:

  This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia. [provided by RefSeq, Jul 2008],

• UniProt:

  Q9UNE0

• Swiss Prot:

  Q9UNE0

• Reactivity:

  Human; Mouse

• Immunogen:

  Synthesized peptide derived from human protein . at AA range: 50-130

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  WB 1:500-2000 ELISA 1:5000-20000

• Molecular Weight:

  49kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  49kD

• Fragment:

  IgG

• Subcellular Location:

  Membrane ; Single-pass type I membrane protein .

• Gene ID (Human):

  10913