EDAR rabbit pAb

CAT: 0855-ES9249-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES9249-01Size:50 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia. [provided by RefSeq, Jul 2008]
Description
This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia. [provided by RefSeq, Jul 2008],
UniProt
Q9UNE0
Swiss Prot
Q9UNE0
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 50-130
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
49kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
49kD
Fragment
IgG
Subcellular Location
Membrane ; Single-pass type I membrane protein .
Gene ID (Human)
10913

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