Products for Research Use Only
RegisterLogin

DYRK3 rabbit pAb

CAT: 0855-ES9026-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0855-ES9026-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
This gene product belongs to the DYRK family of dual-specificity protein kinases that catalyze autophosphorylation on serine/threonine and tyrosine residues. The members of this family share structural similarity, however, differ in their substrate specificity, suggesting their involvement in different cellular functions. The encoded protein has been shown to autophosphorylate on tyrosine residue and catalyze phosphorylation of histones H3 and H2B in vitro. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Description
This gene product belongs to the DYRK family of dual-specificity protein kinases that catalyze autophosphorylation on serine/threonine and tyrosine residues. The members of this family share structural similarity, however, differ in their substrate specificity, suggesting their involvement in different cellular functions. The encoded protein has been shown to autophosphorylate on tyrosine residue and catalyze phosphorylation of histones H3 and H2B in vitro. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
UniProt
O43781
Swiss Prot
O43781
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human protein . at AA range: 1-80
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
64kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
64kD
Fragment
IgG
Subcellular Location
Nucleus . Cytoplasm . Nucleus speckle . Cytoplasmic granule . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Associates with membraneless organelles in the cytoplasm and nucleus (PubMed:29973724) . Shuttles between cytoplasm and stress granules (PubMed:20167603) . Localized predominantly on distinct speckles distributed throughout the cytoplasm of the cell (PubMed:20167603) . At low concentration, showns a homogeneous distribution throughout the cytoplasm and does not condense in speckles. During oxidative and osmotic stress, localizes to stress granules (PubMed:20167603) . .
Gene ID (Human)
8444

Related Products

CatalogName
ES7879-01Dyrk4 rabbit pAb
ES8952-01DYRK2 rabbit pAb
ES4666-01RAB3IP rabbit pAb
ES20751-01Gab1 Rabbit rabbit pAb
ES20703-01JAK2 Rabbit rabbit pAb
ES20758-01ERK1 Rabbit rabbit pAb
ES20830-01ATG14L Rabbit rabbit pAb
ES20829-01ATG4a Rabbit rabbit pAb
ES20658-01NM23A Rabbit rabbit pAb
ES20826-01ATG5 Rabbit rabbit pAb

Alternative Products

CatalogName
E47R9520DYRK3 Rabbit pAb
TA308464DYRK3 Rabbit Polyclonal Antibody
GB114521Anti-DYRK3 Rabbit pAb
NBP3-12695-50ulRabbit Polyclonal DYRK3 Antibody
SL9520R-01Rabbit Anti-DYRK3 antibody
GTR17732306DYRK3 Rabbit Polyclonal Antibody (Biotin)
GTR17752033DYRK3 Rabbit Polyclonal Antibody (PE)
GTR17731095DYRK3 Rabbit Polyclonal Antibody (FITC)
GTR18420615DYRK3 Rabbit Polyclonal Antibody (BF555)
GTR18420612DYRK3 Rabbit Polyclonal Antibody (BF647)

Popular Products