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SL9A3 rabbit pAb

CAT: 0855-ES9006-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES9006-01Size:50 µL
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Background
The protein encoded by this gene is an epithelial brush border Na/H exchanger that uses an inward sodium ion gradient to expel acids from the cell. Defects in this gene are a cause of congenital secretory sodium diarrhea. Pseudogenes of this gene exist on chromosomes 10 and 22. [provided by RefSeq, Mar 2016]
Description
The protein encoded by this gene is an epithelial brush border Na/H exchanger that uses an inward sodium ion gradient to expel acids from the cell. Defects in this gene are a cause of congenital secretory sodium diarrhea. Pseudogenes of this gene exist on chromosomes 10 and 22. [provided by RefSeq, Mar 2016],
UniProt
P48764
Swiss Prot
P48764
Reactivity
Human; Rat
Immunogen
Synthesized peptide derived from human protein . at AA range: 490-570
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
91kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
91kD
Fragment
IgG
Subcellular Location
Apical cell membrane ; Multi-pass membrane protein . In intestinal epithelial cells, localizes to the ileal brush border. Phosphorylation at Ser-663 by SGK1 is associated with increased abundance at the cell membrane. Angiotensin-2 enhances apical expression (By similarity) . .
Gene ID (Human)
6550

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