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ANR28 rabbit pAb

CAT: 0855-ES8968-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES8968-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Function:Putative regulatory subunit of protein phospatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha. Selectively inhibits the phosphatase activity of PPP1C. Targets PPP1C to modulate HNRPK phosphorylation., similarity:Contains 27 ANK repeats., subcellular location:Seems to be excluded from nucleoli., subunit:Protein phospatase 6 (PP6) holoenzyme is proposed to be a heterotrimeric complex formed by the catalytic subunit, a SAPS domain-containing subunit (PP6R) and an ankyrin repeat-domain containing regulatory subunit (ARS) . Interacts with PPP1C and HNRPK. Interacts with PPP6C, SAPS1 and SAPS3.
Description
Function: Putative regulatory subunit of protein phospatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha. Selectively inhibits the phosphatase activity of PPP1C. Targets PPP1C to modulate HNRPK phosphorylation. similarity: Contains 27 ANK repeats. subcellular location: Seems to be excluded from nucleoli. subunit: Protein phospatase 6 (PP6) holoenzyme is proposed to be a heterotrimeric complex formed by the catalytic subunit, a SAPS domain-containing subunit (PP6R) and an ankyrin repeat-domain containing regulatory subunit (ARS). Interacts with PPP1C and HNRPK. Interacts with PPP6C, SAPS1 and SAPS3.
UniProt
O15084
Swiss Prot
O15084
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 980-1060
Target
ANR28
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
-20°C/1 year
Molecular Weight
115kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
115kD
Fragment
IgG
Subcellular Location
Nucleus, nucleoplasm . Seems to be excluded from nucleoli.
Gene ID (Human)
23243

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