Products for Research Use Only
RegisterLogin

Keratin 8 rabbit pAb

CAT: 0855-ES8894-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0855-ES8894-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Keratin 8 (KRT8) Homo sapiens This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
Description
Keratin 8 (KRT8) Homo sapiens This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012],
Product Name Alternative
Keratin, type II cytoskeletal 8 (Cytokeratin-8) (CK-8) (Keratin-8) (K8) (Type-II keratin Kb8)
UniProt
P05787
Swiss Prot
P05787
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human Keratin 8 Polyclonal
Target
Cytokeratin 8
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000
Buffer
-20°C/1 year
Molecular Weight
53kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
53kD
Fragment
IgG
Subcellular Location
Cytoplasm . Nucleus, nucleoplasm . Nucleus matrix .
Other Product Names
Keratin, type II cytoskeletal 8 (Cytokeratin-8) (CK-8) (Keratin-8) (K8) (Type-II keratin Kb8)
Gene ID (Human)
3856

UniProtKB · P05787

Keratin, type II cytoskeletal 8

K2C8_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P05787
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
KRT8
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A8K4H3, B0AZN5, F8VXB4, Q14099, Q14716, Q14717, Q53GJ0, Q6DHW5, Q6GMY0, Q6P4C7, Q96J60
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationGlycoproteinIsopeptide bondMethylationPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Domain

Coiled coil

Cellular component

CytoplasmCytoskeletonIntermediate filamentKeratinNucleus

Disease

Disease variant

Biological process

Host-virus interaction

Related Products

CatalogName
ES15329-01Keratin 77 rabbit pAb
ES4059-01Keratin-pan rabbit pAb
ES8630-01Keratin-pan rabbit pAb
ES8918-01Keratin 5 rabbit pAb
ES7859-01Keratin 37/38 rabbit pAb
ES20107-01Keratin-pan (Acetyl Lys185) rabbit pAb
ES15331-01Keratin 20 (phospho-Ser13) rabbit pAb
ES15333-01Keratin 17 (phospho-Ser44) rabbit pAb
ES2136-01Cytokeratin 8 rabbit pAb
ES2300-01ERK 8 rabbit pAb

Alternative Products

CatalogName
MBS8575897-01KeRatin 5 Rabbit pAb
MBS8541055-01Keratin-pan Rabbit pAb
GTR18598065-01Keratin 31 Rabbit pAb
E47R16952Keratin 80 Rabbit pAb
E51A08379Keratin 6 Rabbit mAb
APA4248-01Keratin 12 Rabbit pAb
MBS8576008-01KeRatin 10 Rabbit pAb
MBS8575894-01KeRatin 4 Rabbit pAb
MBS8575649-01KeRatin 8 Rabbit pAb
MBS4752503-01Keratin 18 Rabbit mAb

Popular Products