COL8A2 rabbit pAb

• Background:

  This gene encodes the alpha 2 chain of type VIII collagen. This protein is a major component of the basement membrane of the corneal endothelium and forms homo- or heterotrimers with alpha 1 (VIII) type collagens. Defects in this gene are associated with Fuchs endothelial corneal dystrophy and posterior polymorphous corneal dystrophy type 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]

• Description:

  This gene encodes the alpha 2 chain of type VIII collagen. This protein is a major component of the basement membrane of the corneal endothelium and forms homo- or heterotrimers with alpha 1 (VIII) type collagens. Defects in this gene are associated with Fuchs endothelial corneal dystrophy and posterior polymorphous corneal dystrophy type 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014],

• Synonyms:

  Collagen alpha-2(VIII) chain (Endothelial collagen)

• Gene ID:

  1296

• UniProt:

  P25067

• Cellular Locus:

  Secreted, extracellular space, extracellular matrix, basement membrane.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Synthesized peptide derived from human COL8A2. at AA range: 611-660

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  WB; ELISA

• Validated Applications:

  WB, ELISA

• Stability:

  -20°C / 1 year

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-2000, ELISA 1:10000-20000

• Molecular Weight:

  80kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  80kD

• Subcellular Location:

  Secreted, extracellular space, extracellular matrix, basement membrane.

• Other Product Names:

  Collagen alpha-2 (VIII) chain (Endothelial collagen)

• Gene ID (Human):

  1296

• SwissProt (Human):

  P25067