Products for Research Use Only
RegisterLogin

TTN rabbit pAb

CAT: 0855-ES8758-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0855-ES8758-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
This gene encodes a large abundant protein of striated muscle. The product of this gene is divided into two regions, a N-terminal I-band and a C-terminal A-band. The I-band, which is the elastic part of the molecule, contains two regions of tandem immunoglobulin domains on either side of a PEVK region that is rich in proline, glutamate, valine and lysine. The A-band, which is thought to act as a protein-ruler, contains a mixture of immunoglobulin and fibronectin repeats, and possesses kinase activity. An N-terminal Z-disc region and a C-terminal M-line region bind to the Z-line and M-line of the sarcomere, respectively, so that a single titin molecule spans half the length of a sarcomere. Titin also contains binding sites for muscle associated proteins so it serves as an adhesion template for the assembly of contractile machinery in muscle cells. It has also been identified as a structural protein for chromosomes.
Description
This gene encodes a large abundant protein of striated muscle. The product of this gene is divided into two regions, a N-terminal I-band and a C-terminal A-band. The I-band, which is the elastic part of the molecule, contains two regions of tandem immunoglobulin domains on either side of a PEVK region that is rich in proline, glutamate, valine and lysine. The A-band, which is thought to act as a protein-ruler, contains a mixture of immunoglobulin and fibronectin repeats, and possesses kinase activity. An N-terminal Z-disc region and a C-terminal M-line region bind to the Z-line and M-line of the sarcomere, respectively, so that a single titin molecule spans half the length of a sarcomere. Titin also contains binding sites for muscle associated proteins so it serves as an adhesion template for the assembly of contractile machinery in muscle cells. It has also been identified as a structural protein for chromosomes.
UniProt
Q8WZ42
Swiss Prot
Q8WZ42
Reactivity
Human; Mouse; Rat
Immunogen
Synthetic peptide from human protein at AA range: 161-210
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
IHC-p 1:50-200, ELISA 1:10000-20000
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Cytoplasm . Nucleus .
Other Product Names
Titin (EC 2.7.11.1; Connectin; Rhabdomyosarcoma antigen MU-RMS-40.14)
Gene ID (Human)
7273

Related Products

CatalogName
ELK2138-01Human TTN (Titin) ELISA Kit
ELK2138MS-01Human TTN (Titin) Microsample ELISA Kit
ELK0760-01Human Anti-TTN (Anti-Titin Antibody) ELISA Kit
ES4666-01RAB3IP rabbit pAb
ES20751-01Gab1 Rabbit rabbit pAb
ES20703-01JAK2 Rabbit rabbit pAb
ES20758-01ERK1 Rabbit rabbit pAb
ES20830-01ATG14L Rabbit rabbit pAb
ES20829-01ATG4a Rabbit rabbit pAb
ES20658-01NM23A Rabbit rabbit pAb

Alternative Products

CatalogName
RTR015Rabbit-to-Rabbit Blocking Reagent
AR05252PU-NRabbit IgG Rabbit Protein
AR05110PU-NRabbit IgM Rabbit Protein
NBP1-71681Rabbit Normal Rabbit Serum
OORA00605-100MLRabbit
KA2017Rabbit Rabbit IgG ELISA Kit
MBS9512780-01JAK2 Rabbit Rabbit Polyclonal Antibody
MBS9512768-01VEGF Rabbit Rabbit Polyclonal Antibody
MBS9518120-01ATG4c Rabbit Rabbit Polyclonal Antibody
MBS9518118-01ATG4a Rabbit Rabbit Polyclonal Antibody

Popular Products