IL-27A rabbit pAb

• Background:

  The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A) . It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4 (+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4 (+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR) . [provided by RefSeq, Jul 2008]

• Description:

  The protein encoded by this gene is one of the subunits of a heterodimeric Cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4 (+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4 (+) T cells. The biological effects of this Cytokine are mediated by the class I Cytokine receptor (WSX1/TCRR). [provided by RefSeq, Jul 2008],

• UniProt:

  Q8NEV9

• Swiss Prot:

  Q8NEV9

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Synthetic peptide from human protein at AA range: 1-50

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  IHC; IF; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  IHC-p 1:50-200, ELISA 1:10000-20000

• Storage Conditions:

  -20°C/1 year

• Fragment:

  IgG

• Subcellular Location:

  Secreted . Does not seem to be secreted without coexpression of EBI3.

• Other Product Names:

  Interleukin-27 subunit alpha (IL-27 subunit alpha; IL-27-A; IL27-A; p28)

• Gene ID (Human):

  246778