IL-2 rabbit pAb

CAT: 0855-ES2611-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES2611-01Size:50 µL
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Background
The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7) . The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. [provided by RefSeq, Jul 2008]
Description
The protein encoded by this gene is a secreted Cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this Cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. [provided by RefSeq, Jul 2008],
Product Name Alternative
IL2; Interleukin-2; IL-2; T-cell growth factor; TCGF; Aldesleukin
UniProt
P60568
Swiss Prot
P60568
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human IL-2. AA range:16-65
Target
IL-2
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. IF 1:100-300 Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
15kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
15kD
Fragment
IgG
Subcellular Location
Secreted.
Other Product Names
IL2; Interleukin-2; IL-2; T-cell growth factor; TCGF; Aldesleukin
Gene ID (Human)
3558

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