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IL-19 rabbit pAb

CAT: 0855-ES8710-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES8710-01Size:50 µL
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Background
The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3) . A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. [provided by RefSeq, Jul 2008]
Description
The protein encoded by this gene is a Cytokine that belongs to the IL10 Cytokine subfamily. This Cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar Cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this Cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. [provided by RefSeq, Jul 2008],
UniProt
Q9UHD0
Swiss Prot
Q9UHD0
Reactivity
Human; Rat
Immunogen
Synthetic peptide from human protein at AA range: 51-100
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000, IHC-p 1:500-200, ELISA 1:10000-20000
Molecular Weight
20kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
20kD
Fragment
IgG
Subcellular Location
Secreted.
Other Product Names
Interleukin-19 (IL-19; Melanoma differentiation-associated protein-like protein; NG.1)
Gene ID (Human)
29949

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