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CD297 rabbit pAb

CAT: 0855-ES8695-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0855-ES8695-02Size:100 µL
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Background
This gene encodes a protein that contains a mono-ADP-ribosylation (ART) motif. It is a member of the ADP-ribosyltransferase gene family but enzymatic activity has not been demonstrated experimentally. Antigens of the Dombrock blood group system are located on the gene product, which is glycosylphosphatidylinosotol-anchored to the erythrocyte membrane. Allelic variants, some of which lead to adverse transfusion reactions, are known. [provided by RefSeq, Jul 2008]
Description
This gene encodes a protein that contains a mono-ADP-ribosylation (ART) motif. It is a member of the ADP-ribosyltransferase gene family but enzymatic activity has not been demonstrated experimentally. Antigens of the Dombrock blood group system are located on the gene product, which is glycosylphosphatidylinosotol-anchored to the erythrocyte membrane. Allelic variants, some of which lead to adverse transfusion reactions, are known. [provided by RefSeq, Jul 2008],
UniProt
Q93070
Swiss Prot
Q93070
Reactivity
Human; Rat; Mouse
Immunogen
Synthetic peptide from human protein at AA range: 181-230
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
IHC-p 1:50-200, ELISA 1:10000-20000
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Cell membrane; Lipid-anchor, GPI-anchor.
Other Product Names
Ecto-ADP-ribosyltransferase 4 (EC 2.4.2.31; ADP-ribosyltransferase C2 and C3 toxin-like 4; ARTC4; Dombrock blood group carrier molecule; Mono (ADP-ribosyl) transferase 4; NAD (P) (+) --arginine ADP-ribosyltransferase 4; CD antigen CD297)
Gene ID (Human)
420

UniProtKB · Q93070

Ecto-ADP-ribosyltransferase 4

NAR4_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q93070
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ART4
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.4.2.31
Processing
Precursor
Secondary accessions
Q9BZ50, Q9BZ51, Q9HB06
Protein keywords

Molecular function

Blood group antigenGlycosyltransferaseNucleotidyltransferaseTransferase

Cellular component

Cell membraneMembrane

PTM

Disulfide bondGlycoproteinGPI-anchorLipoprotein

Ligand

NADNADP

Technical term

Proteomics identificationReference proteome

Domain

Signal

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