PD-L2 rabbit pAb

• Background:

  Function:Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production., induction:Up-regulated by IFNG stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL4., similarity:Belongs to the immunoglobulin superfamily. BTN/MOG family., similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain., similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain., subunit:Interacts with PDCD1., tissue specificity:Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus.

• Description:

  Function: Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and Cytokine production. induction: Up-regulated by IFNG stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL4. similarity: Belongs to the immunoglobulin superfamily. BTN/MOG family. similarity: Contains 1 Ig-like C2-type (immunoglobulin-like) domain. similarity: Contains 1 Ig-like V-type (immunoglobulin-like) domain. subunit: Interacts with PDCD1. tissue specificity: Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus.

• UniProt:

  Q9BQ51

• Swiss Prot:

  Q9BQ51

• Reactivity:

  Human; Rat; Mouse

• Immunogen:

  Synthetic peptide from human protein at AA range: 31-80

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; IHC; IF; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  WB 1:500-2000, IHC-p 1:50-200, ELISA 1:10000-20000

• Molecular Weight:

  30kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  30kD

• Fragment:

  IgG

• Subcellular Location:

  [Isoform 3]: Secreted .; [Isoform 2]: Endomembrane system ; Single-pass type I membrane protein .; [Isoform 1]: Cell membrane ; Single-pass type I membrane protein .

• Other Product Names:

  Programmed cell death 1 ligand 2 (PD-1 ligand 2; PD-L2; PDCD1 ligand 2; Programmed death ligand 2; Butyrophilin B7-DC; B7-DC; CD antigen CD273)

• Gene ID (Human):

  80380