Dsg1 rabbit pAb
CAT:
855-ES8660-02
Size:
100 μL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Dsg1 rabbit pAb
- Description: This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma. [provided by RefSeq, Feb 2015],
- Synonyms: Desmoglein-1 (Cadherin family member 4;Desmosomal glycoprotein 1;DG1;DGI;Pemphigus foliaceus antigen)
- Gene ID: 1828
- UniProt: Q02413
- Cellular Locus: Cell membrane ; Single-pass type I membrane protein. Cell junction, desmosome.
- Host: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Immunogen: Synthetic peptide from human protein at AA range: 30-90
- Clonality: Polyclonal
- Validated Applications: WB, IHC, IF, ELISA
- Stability: 1 year
- Concentration: 1 mg/mL
- Dilution: WB 1:500-2000,IHC-p 1:500-200, ELISA 1:10000-20000
- Molecular Weight: 160kD
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.